GLP-1 Treatment Optimizer Should you switch, stay, or adjust?
Answer 5 questions about your current medication and results. Get a personalized clinical recommendation — with the biological reasoning behind it — based on real trial data.
Not a generic comparison chart
Not a tracking app
Is a personalized recommendation
Step 1 of 50%
MedicationDurationResultsSymptomsProfile
💊 What are you currently taking?
Select your current GLP-1 medication and dose level
💊
Semaglutide — low dose
0.25mg or 0.5mg/week (Ozempic, compounded sema)
Building tolerance / early therapeutic
💊
Semaglutide — mid dose
1.0mg or 1.7mg/week
~10–13% avg weight loss at this range
💊
Semaglutide — max dose
2.4mg/week (Wegovy level)
~15% avg weight loss at max dose
💊
Tirzepatide — low dose
2.5mg or 5mg/week (Mounjaro, compounded tirz)
Building tolerance / early therapeutic
💊
Tirzepatide — mid dose
7.5mg or 10mg/week
~17–20% avg weight loss at this range
💊
Tirzepatide — max dose
12.5mg or 15mg/week
~22% avg weight loss at max dose
💡
Not started yet
Researching first medication
Get a starting recommendation
⏸
Recently stopped
Was on GLP-1, now off it
Managing regain or restarting
📅 How long have you been on this medication?
And how has your dose changed over time?
🕒
Under 4 weeks
Just started
📅
1–3 months
Early treatment
📈
3–6 months
Established treatment
🎉
6–12 months
Long-term treatment
⭐
Over 12 months
Extended treatment
→
I recently switched
Changed from another GLP-1
⚖ How are your results?
Be specific — this is the most important step for accurate recommendation
Weight lost: not sure yet
0 lbs20406080+
Months on treatment: not sure yet
Just started6 mo12 mo18 mo24 mo
What best describes your current progress?
📈
Still losing well
Consistent progress, satisfied
↭
Loss has slowed
Was working, now slower
⎯
Complete plateau
No loss for 6+ weeks
↗
Regaining weight
Scale going up despite medication
❌
Never worked well
Minimal results from start
🕒
Too early to tell
Under 8 weeks / still titrating
📋 Current side effects
Check all that apply — even mild ones
Nausea or vomitingEspecially around injection day or after eating
Severe constipationAffecting daily life, difficult to manage
Significant fatigueMore tired than expected, low energy
Hair loss / thinningNoticeable shedding beyond normal
Muscle loss / weaknessLosing strength, clothes fit differently despite weight loss
Injection site reactionsPersistent pain, redness, or lumps at injection sites
Reflux / heartburnWorsened or new acid reflux symptoms
No significant side effectsTolerating well overall
👥 Your health profile
Select all that apply — this calibrates the recommendation for your biology
Type 2 diabetes or prediabetesInsulin resistance is likely a significant factor
PCOS (polycystic ovary syndrome)Insulin resistance drives both PCOS and weight gain
Perimenopausal or postmenopausalHormonal changes reduce GLP-1 effectiveness without HRT
Significant cardiovascular historyHeart disease, prior heart attack, or stroke
Currently on HRT (hormone replacement therapy)Estrogen therapy amplifies GLP-1 effectiveness
Under significant chronic stress / poor sleepCortisol blocks GLP-1 weight loss effects
Eating less than 800 calories/daySevere restriction causes muscle loss that stalls results
None of the above
Recommendation confidence
confidence
🔬 Clinical signals from your profile
🎯 Your personalized action plan
Your options — clinical comparison
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Clinical data sources: STEP 1–4 trials (semaglutide), SURMOUNT-1/2/5 trials (tirzepatide), SELECT cardiovascular trial. Individual results vary significantly. This tool provides general guidance based on population-level data — not personalized medical advice. Always consult your prescribing physician before changing medications.
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