Excess weight directly lowers testosterone and impairs blood flow. See your estimated testosterone increase from weight loss, based on real clinical research — not guesswork.
Mendelian randomization study, 2024
Frontiers in Endocrinology
ENDO 2026 presentation
Step 1 of 30%
Your basics
Used only to calculate your estimate — nothing is saved or sent anywhere.
Testosterone naturally declines ~1-2% per year after age 30 — your age calibrates the estimate.
Testosterone & symptoms
If you don't know your number, that's completely fine — skip it.
Normal range is roughly 300-1000 ng/dL, but symptoms matter more than the number alone.
Which symptoms apply to you?
Erectile difficulty or inconsistencyTrouble achieving or maintaining erections
Low libidoReduced interest in sex compared to before
Persistent fatigueLow energy despite adequate sleep
Difficulty building muscleReduced gains despite consistent training
Brain fog / reduced motivationMental sharpness or drive feels diminished
None of theseJust curious about the numbers
A bit more context
This refines your estimate using the actual research mechanisms.
Type 2 diabetes or prediabetes?
🔮
Yes
Diagnosed or borderline
✓
No
Not diagnosed
Current activity level
🛏
Sedentary
Little to no exercise
🚶
Lightly active
1-2 sessions/week
💪
Moderately active
3-4 sessions/week
🔥
Very active
5+ sessions/week
Estimated testosterone increase
+0ng/dL
🩲 Estimated erectile function impact
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Based on a 2024 Mendelian randomization study: GLP-1 receptor agonist use was associated with a 51% reduction in ED risk (OR 0.493), mediated through improved vascular health, reduced diabetes risk, and weight loss.
🔬 Why this happens — the mechanism
📅 What to expect, and when
🎯 Your options
💊 Start with GLP-1 weight loss
Address the root cause — visceral fat — directly. DirectMeds offers physician-supervised compounded semaglutide and tirzepatide.
How this estimate is calculated: This tool applies published population-level research findings (testosterone increases of 50-100+ ng/dL per published studies on men losing 10%+ body weight, and the 2024 Mendelian randomization ED risk reduction) to your inputs. This is a statistical estimate based on group-level clinical data, not a personalized medical prediction — individual results vary significantly based on genetics, baseline hormone levels, and overall health. This tool does not diagnose low testosterone or ED. A blood test and physician evaluation are required for an actual diagnosis.
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